Were season 22 to reprise oneGrey’s Anatomyseason 19 story, it could make Meredith’s Alzheimer’s study arc much more powerful.Grey’s Anatomyseasons 20 and 21 have made Meredith’s Alzheimer’s research her biggest focus, with it bringing the most consequential developments since Meredith’s departure from Seattle.Grey’s Anatomyseason 22can nevertheless use another story to support Meredith’s study.
Since Jackson offered Meredith the solution to her problems, giving her a place to study the illness that was always inextricably linked to her history in the city where Zola’s school was, studying Alzheimer’s centered Meredith’s every move. WithGrey’s Anatomyseason 21’s endingintroducing Meredith spending more time in Seattle, one forgotten story can make Meredith’s advocacy more powerful.
Simone’s Grandma’s Alzheimer’s Was Very Important In Grey’s Anatomy Season 19 But Has Since Been Forgotten
What defined Simone’s story whenGrey’s Anatomyseason 19 introduced her was her mother dying giving birth to her at Grey Sloan Memorial and her grandmother being diagnosed with Alzheimer’s, which was especially impactful because she had been Simone’s mother figure her whole life, having barely met her mother. However,Grey’s Anatomysubsequently made Simone’s grandmother a more marginal figure.
The ever-present drama ofLucas and Simone’s relationship dominatedGrey’s Anatomyseason 21, making the need for a breakup extremely clear. With the two lovebirds repeatedly butting heads, seemingly breaking up, only to get back together in the next episode,Grey’s Anatomyseason 21 had little time for Simone’s grandmother, except for when Lucas mentioned visiting her.
Grey’s Anatomyseason 19 undoubtedly set up Simone’s grandmother as an important part of her life. With season 21 focusing greatly on Simone’s personal and professional progress, it would make sense that Simone would share that part of her life, beyond Lucas, with her grandmother.
Grey’s Anatomyseason 22 premieres on ABC at 10pm ET on Thursday, June 29, 2025.
Grey’s Anatomyseason 22 can fix season 21’s mistake by having Simone’s grandmother play a bigger role, which in turn can benefit Meredith’s Alzheimer’s story. This can also make Simone and Meredith’s connection come full circle after season 19 hinted at the former being the latter’s replacement because of their history with Grey Sloan and Alzheimer’s importance in their lives.
How Grey’s Anatomy Season 22 Bringing Back Simone’s Grandma Can Link To Meredith’s Alzheimer Study
Meredith and Amelia’s Alzheimer’s research went through major upheavals inGrey’s Anatomyseason 21. Between Catherine and Jackson’s cease-and-desist letters and the difficulties finding new backers,Meredith and Amelia spent most of season 21 in limbo, at least when their study was concerned.Grey’s Anatomyseason 21, episode 12 proved groundbreaking for how it gave their research a new direction.
By realizing that their prospective financiers didn’t understand the importance of studying Alzheimer’s in women,Grey’s Anatomyseason 21, episode 12 pushed Meredith to decide to fund the study by herself. This solved the problem they had been facing since publishing their findings inGrey’s Anatomyseason 20’s finale, and it tailored their research like they wanted.
Simone’s grandmother returning inGrey’s Anatomyseason 22 can show what Meredith meant when she faced those evaluating her funding proposal inGrey’s Anatomyseason 21, episode 12, through an emotional story. This way, Simone’s bond with her grandma would return front and center, and Meredith and Amelia’s research would also have a recognizable face, making it even more urgent.
